Rapamycin
Longevity Lab
It’s time to speed things up!
Rapamycin is the most promising longevity compound that has ever been discovered. It's time to speed up the research around mTOR inhibitors such as Rapamycin and start engineering longevity cocktails based on them which will increase the chance for us to live well and beyond 100(0) years. That's why we've launched this community-driven lab, where we'll collaborate with other labs, researchers, organizations and with you to make this vision a reality. Join us today and let's work together to create a future where everyone can live a radically longer and healthier life.
(Plus get this great Rapamycin overview sheet)
A revolutationarystep forward
Together as a community we can accelerate longevity science around Rapamycin and other mTOR inhibitors. Our initial project is to partner with Ora Biomedical and coordinate a comprehensive lifespan analysis of over 600 mTOR inhibitors in the roundworm 'Caenorhabditis elegans'. To achieve this quickly and in a cost-effective way, we will use Ora Biomedical's revolutionary wormbot platform, which combines robotics and AI to perform massively high-throughput longevity analysis in roundworms.
High-efficient lifespan analysis
of 601 mtor inhibitors
Project: In this revolutionary project the Rapamycin Longevity Lab will coordinate a lifespan analysis of 601 mTOR inhibitors in the roundworm ‘C. elegans’. No one has delivered anything close to the big magnitude of unique data around mTOR inhibitors which this project will deliver
Why screen mTOR inhibitors? Rapamycin is an mTOR inhibitor and is the only compound that has shown very good longevity effects in multiple species. Everything from yeast, worms, flies to mice show improved healthy lifespan with rapamycin treatment. This is unique when it comes to longevity interventions. But there is a big gap in the literature around how good Rapamycin is compared to other mTOR inhibitors. While many mTOR inhibitors have been developed, no systematic effort exists to find the most effective mTOR inhibitors for improving healthy lifespan. This is something we need an answer on and this project is an important first step in that direction. The end goal is improved human longevity.
Use of innovative technology: The world leading Rapamycin researcher Matt Kaeberlein co-founded the company Ora Biomedical. In this project their innovative WormBot-AI technology will be used to screen the mTOR inhibitors in a highly-efficient and cost-efficient way.
Public data: The lifespan data from this screening will be publicly available on Ora Biomedical’s online database for free. This data will be a valuable source for taking longevity research around mTOR inhibitors to the next level.
Time of delivery: The goal is to start the project as soon as it is fully funded. Once funded, data will start being released within three months.
Project budget: 50 000 USD for the first sub project where 301 of the 601 mTOR inhibitors are screened. This is a very low price for the big amount of data we will get and for moving the longevity field forward. Ora Biomedical provides the project to the public and all the money will go directly to them to conduct and cover the costs for the screening of the mTOR inhibitors. Rapamycin Longevity Lab will coordinate and project lead this project and will not take part in any commission or provision.
Sponsoring spots for funding the project
$10k gold, $5k silver or $1k sponsor
Gold sponsors
Silver sponsors
Sponsors
Media supporters
Contact Krister Kauppi to help
out or donate to the project
Importance of testing combinations
Longevity Lab
I get frustrated and disappointed that the research progress around the best and most promising longevity compound Rapamycin is moving way too slow forward. One reason for this is that there is no valid patent for Rapamycin anymore and this makes it hard to capitalize on the substance. My philanthropic personality just can't accept this situation so I will do what I can together with other passionate people to push mTOR inhibitors such as Rapamycin up to the top of the hill. After that I think things will start to accelerate quite fast almost by themselves. So my N=1 experiment around Rapamycin, my posts on social media about mTOR inhibition and the launch of the Rapamycin Longevity Series podcast are my ways to contribute to the field. Now it’s time to take the next step and launch the Rapamycin Longevity Lab and start pushing the snowball forward together with other people and organizations.
Krister Kauppi
Founder of the Rapamycin Longevity Lab
