Rapamycin
Longevity Lab It’s time to speed things up!

Rapamycin is the most promising longevity compound that has ever been discovered. It's time to speed up the research around mTOR inhibitors such as Rapamycin and start engineering longevity cocktails based on them which will increase the chance to live well and beyond 100(0) years. That's why we've launched this community-driven lab, where we'll collaborate with other labs, researchers, organizations and with you to make this vision a reality. Join us today and let's work together to create a future where everyone can live a radically longer and healthier life.

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(Plus get this great Rapamycin overview sheet)

A revolutationarystep forward

Together as a community we can accelerate longevity science around Rapamycin and other mTOR inhibitors. Our initial project is to partner with Ora Biomedical and coordinate a comprehensive lifespan analysis of over 500 mTOR inhibitors in the roundworm 'Caenorhabditis elegans'. To achieve this quickly and in a cost-effective way, we will use Ora Biomedical's revolutionary wormbot platform, which combines robotics and AI to perform massively high-throughput longevity analysis in roundworms.

Project overview

High-efficient lifespan analysis
of 568 mtor inhibitors

Project: In this revolutionary project the lab will coordinate a lifespan analysis of 568 mTOR inhibitors in the roundworm 'Caenorhabditis elegans'. No one has delivered anything close to the big magnitude of unique data around mTOR inhibitors which this project will deliver.

Why screen mTOR inhibitors? Rapamycin is an mTOR inhibitor and is the only compound that has shown very good longevity effects in multiple species. Everything from yeast, worms, flies to mice. This is unique when it comes to longevity interventions. But there is a big gap in the literature around how good Rapamycin is compared to other mTOR inhibitors. This is something we need an answer on and this project is an important first step in that direction.

Use of innovative technology: We have built up a close partnership with the world's leading Rapamycin researcher Matt Kaeberlein and his company Ora Biomedical. In this project their groundbreaking wormbot technology will be used to screen the mTOR inhibitors in a high-efficient and cost-efficient way.

Public data: The lifespan data from this screening will be publically available on Ora Biomedical’s online database for free. This data will be a valuable source for taking longevity research around mTOR inhibitors to the next level.

Time of delivery: The goal is to start the project as soon as it is fully funded. When the project is started it will take around 3 months before we get the data.

Project budget: 50 000 USD for the first sub project where 284 of the 568 mTOR inhibitors are screened. This is a very low price for the big amount of data we will get. Ora Biomedical provides the project to the public and all the money will go directly to them to conduct and cover the costs for the screening of the mTOR inhibitors. Rapamycin Longevity Lab will coordinate and project lead this project and will not take part in any commission or provision.

The Wormbot

Importance of testing combinations